September (Zoom) 09/14/2022
How to Use the Software that Controls Cellular Differentiation
Epigenetic mechanisms control how cells "read" your DNA. Many of these mechanisms are reversible, making them prime candidates for cancer therapies. Dr. Reich's lab has identified how a key player in this process--the DNA methyltransferase 3A--is controlled by its interactions with partner proteins. They discovered small molecules that help control this process when it goes wrong, particularly in various forms of leukemia.
Dr. Norbert Reich, Distinguished Professor, UCSB Department of Chemistry and Biochemistry
Dr. Reich started the drug company EpiGenX and UCSB's largest science outreach program, SciTrek. He received his BS in Biochemistry from UC Berkeley and his Ph.D. in Medicinal Chemistry from UC San Francisco. He is an active bike rider, sailor, and consumer of good wine. He lives with his wife, two pugs, a cat, and an Amazon parrot. link: https://reich.chem.ucsb.edu